Gestational Pemphigoid: Placental Morphology and Function
نویسندگان
چکیده
منابع مشابه
Gestational pemphigoid: placental morphology and function.
Gestational pemphigoid (PG), a very rare pregnancy-associated bullous dermatosis, is associated with adverse pregnancy outcome (miscarriage, preterm delivery, foetal growth restriction). The major antigen in PG is collagen XVII (BP180). PG autoantibodies cross-react with collagen XVII in the skin and have been suggested to cause placental failure. On this basis, we evaluated clinical outcome an...
متن کاملGestational pemphigoid
Gestational pemphigoid is a rare pruritic bullous pregnancy associated dermatosis caused by autoantibodies against placental and dermal collagen XVII. Clinically, it is characterized by severe pruritus and blisters on abdominal skin and extremities. Immunofluorescence analysis of perilesional skin is used in the diagnostics and maternal serum BP180-levels reflect the disease activity. Topical s...
متن کاملComparative placental morphology and function.
The distinction between histiotrophic nutrition (in which local macromolecules are chiefly responsible for the maintenance of the embryo) and hemotrophic nutrition (which results from a transfer of material between the maternal and fetal circulations) is made. Placentation in a number of commonly used laboratory animals and in man is described, and it is shown that dependence upon histiotroph a...
متن کامل[Changes in placental morphology of small for gestational age newborns].
OBJECTIVE To verify changes in placental morphology of small for gestational age newborns, considering that the occurrence of placental alterations is more frequent in small for gestational age (SGA) infants than in appropriate for gestational age (AGA) infants. METHODS Fifty SGA newborns were included in a cross-sectional study, which involved gross anatomy and light microscopy of placenta, ...
متن کاملEffects of Diet and Metformin on placental morphology in Gestational Diabetes Mellitus
OBJECTIVE To evaluate the effects of diet control and Metformin on placental morphology in gestational diabetes mellitus (GDM). METHODS After written informed consent 62 GDMs were enrolled. According to WHO criteria, 30 cases of GDMs with blood sugar level <130 mg/dl, were assigned Group B (2000-2500Kcal/day and 30 minute walk thrice weekly were kept on diet control and 32 cases of GDM with b...
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ژورنال
عنوان ژورنال: Acta Dermato Venereologica
سال: 2013
ISSN: 0001-5555
DOI: 10.2340/00015555-1370